Oral: 4 to 11 years: 1
ORS = oral rehydration solution; WHO =
Uses Warnings Before taking Side effects Dosage Interactions FAQ What is ondansetron? Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting
A 2013 overview identified four studies that evaluated the efficacy of single-dose oral ondansetron compared to placebo in children with gastroenteritis presenting
Generic: 4 mg/5 mL (50 mL) Tablet, Oral, as hydrochloride [strength expressed as base]: Zofran: 4 mg, 8 mg Generic: 4 mg, 8 mg, 24 mg Tablet
Indications and dose Gastro-enteritis, management of vomiting By mouth Child 6 months–17 years 100–150 micrograms/kg every 8–12 hours (max
Ondansetron injection USP, 2 mg/mL is a clear, colorless, nonpyrogenic, sterile solution available as a 2 mL single-dose vial
Contraindications
Highly emetogenic chemotherapy: 24 mg as a single dose, given 0
Never give a double dose, no matter how much time has passed since the previous once
18 If the child vomited within 15 min of administration, the same dose was repeated once
15mg/kg or
of children n= 28)
If the child is unable to tolerate oral intake or is unwell, start IV fluids with glucose at maintenance rate as per hypoglycaemia guideline
In children with gastroenteritis and dehydration, a single dose of oral ondansetron reduces vomiting and facilitates oral rehydration and may thus be well suited for use in the emergency Ondansetron is a medicine that is used to treat or prevent nausea (feeling sick, upset stomach) and vomiting (throwing up)
If it is close to the time for your next dose, skip the missed dose and go back to your normal time
24 of 83 children receiving placebo; P Ondansetron is one of the medications most commonly used for the empiric treatment of nausea and vomiting
Ondansetron is available in many different dosage forms like tablet, injection, syrup, films, oral drops
In these trials, 58% of the 170 evaluable patients had a complete response (no emetic episodes) on Day 1
3 mg/kg/day (Max: 100 mg/day) Q6-12 (100,000 units/mL) Infants: 2 mL/dose QID Children & Adolescents: 5 mL/dose QID Oxacillin 100