Long-Term Effects of Spironolactone on Kidney
Spironolactone increased the absolute risk of worsening kidney function (absolute risk difference for total population, +9%; 95% CI, +4% to +14%; p < 0
In conclusion, this study has shown that spironolactone may reduce proteinuria and retard renal progression in chronic kidney disease patients
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Read on to learn about 6 types of common medications that may be damaging your kidneys
Examples include aspirin (Bayer), ibuprofen ( Advil ), and naproxen (Aleve)
Key takeaways: In July 2021, the FDA approved Bayer’s Kerendia (finerenone) to treat chronic kidney disease (CKD) in people with type 2 diabetes
Yang et al
Spironolactone is used to treat build-up of fluid in your body caused by: heart failure; liver disease – it treats build-up of fluid in your abdomen, called ascites; kidney disease – it treats a condition that causes your kidneys to leak large amounts of protein into your pee, called nephrotic syndrome; Experimental evidence suggests that aldosterone contributes to progressive kidney disease
You’re asking if spironolactone damages your kidneys, and if it safe to take for 6 months to a year
Oral spironolactone can cause high potassium in your blood, especially if you have kidney disease
Unlike other types of diuretic, spironolactone does not make your body lose potassium
Your kidneys are responsible for filtering out toxins and waste from your blood
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The Food and Drug Administration (FDA) has approved furosemide to treat conditions with volume overload and edema secondary to congestive heart failure exacerbation, liver failure, or renal failure, including the nephrotic syndrome
Spironolactone should only be used to treat hypertension in those who are starting step 4 treatment for resistant hypertension and who have a blood potassium level of 4
Serious side effects include kidney failure, liver dysfunction, vasculitis, and low platelets
Half of all deaths in patients with chronic kidney disease (CKD) arise from cardiovascular causes
Although adding spironolactone to renin-angiotensin system blockers reduces albuminuria in adults with chronic kidney disease and type 2 diabetes, it increases the risk of hyperkalemia