ACTOPLUS MET may be titrated up to a maximum daily dose of 45 mg of pioglitazone and 2550 mg of metformin
DESCRIPTION ACTOPLUS MET (pioglitazone hydrochloride and metformin hydrochloride) tablets contain two oral antihyperglycemic drugs used in the management
diabetes mellitus, type 2 [individualize dose PO qd-tid] Take this medication by mouth as directed by your doctor, usually once or twice daily with meals to decrease stomach upset
It’s FDA-approved to help control blood sugar levels in adults with type 2 diabetes
When added to metformin, the triple combination therapy of alogliptin (pooled dose; 12
In the combination therapy actos is prescribed in a dose of 15 mg or 30 mg 1 time / day
Serious side effects
1,000 mg/15 mg; 1,000 mg/30 mg; Type 2 Diabetes Mellitus
For oral dosage form (tablets): Adults—At first, 1 tablet one or two times a day with food
Pioglitazone is used with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes
The maximum recommended dosage is 45 mg/2550 mg
ACTOS is a thiazolidinedione and an agonist for peroxisome proliferator-activated receptor (PPAR) gamma indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings
Individualize the starting dose based on the patient's current regimen and adjust the dosing based on effectiveness and tolerability while not exceeding the maximum recommended daily dose of pioglitazone 45 mg and metformin 2550 mg
5 mg - 1000 mg
Dose titration: Increase in 500 mg increments weekly as tolerated
Two clinical studies were conducted with ACTOS in combination with metformin
Duetact can cause the same side effects as Actos, but it can also cause side effects of
Actos is used to treat the following conditions: Diabetes, Type 2; Metabolic Dysfunction-Associated Steatotic Liver Disease (off-label) metformin
Some people taking this medicine have had bladder cancer, but it is not clear if pioglitazone was the actual cause
See Contraindications