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This activity describes the indications, action, and contraindications for prazosin as a valuable agent in treating and managing various conditions for which it has Description Prazosin is a member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively
862 Da Monoisotopic mass 419
Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988
Abstract The three-dimensional solid-state structures of prazosin hydrochloride, C19H22N5O4+ · Cl− (A), and prazosin free base, C19H21N5O4 (B)
Closely related structural analogues of prazosin have been synthesised and tested for inhibition and activation of Transport-P in order to identify the structural
Chemical names and formulas
Prazosin may cause serious side effects
In contrast to MCA‐NAT and 2‐I‐MCA‐NAT, two conformations of prazosin could be modeled into the active site since the density was too ambiguous for assignment of only one orientation
Embed URL USES: Prazosin is used with or without other medications to treat high blood pressure
Interactions between the side chains of amino acids lead to the formation of the tertiary structure, and bonds form between them as the protein folds
Synthesis, Pharmacological Evaluation, and Structure−Activity Relationship and Quantitative Structure−Activity Relationship Studies on Novel Derivatives of 2,4-Diamino AlphaFold is an AI system developed by DeepMind that predicts a protein’s 3D structure from its amino acid sequence
It is a quinazoline derivative that acts as a competitive alpha1-antagonist
Visit ChemicalBook To find more Prazosin hydrochloride (19237-84-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes
Pharmacologic studies have demonstrated that the vasodilator action of prazosin Abstract
A and B crystallize in triclinic P-1 and monoclinic Cc space groups, respectively, with one structural unit per asymmetric part
8(7): e69648
2024-02-17
The three‐dimensional solid‐state structures of prazosin hydrochloride, C19H22N5O4+ · Cl− (A), and prazosin free base, C19H21N5O4 (B), have been determined by synchrotron X‐ray powder diffraction
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SMILES (Simplified Molecular Input Line Entry System) is a chemical notation that allows a user to represent a chemical structure in a way that can be used by the computer
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